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Self-assembly of vascularized tissue to support tumor explants in vitro

Testing the efficacy of cancer drugs requires functional assays that recapitulate the cell populations, anatomy and biological responses of human tumors. Although current animal models and in vitro cell culture platforms are informative, they have significant shortcomings. Mouse models can reproduce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Integr Biol (Camb)
Hauptverfasser: Bazou, Despina, Maimon, Nir, Gruionu, Gabriel, Munn, Lance L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155578/
https://ncbi.nlm.nih.gov/pubmed/27787529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ib00108d
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