Chemical modification of simian virus 40 DNA by reaction with a water-soluble carbodiimide.

Superhelical simian virus 40 (SV40) DNA I can be modified with N-cyclohexyl-N'-beta-(4 methylmorpholinium)ethylcarbodiimide (CMC). The reaction produces an increase in the sedimentation velocity of DNA I from 21 to 22.5S and a decrease in its buoyant density in CsCl from 1.694 to 1.688. A compa...

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Bibliographic Details
Main Authors: Lebowitz, J, Garon, C G, Chen, M C, Salzman, N P
Format: Artigo
Language:Inglês
Published: 1976
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC515539/
https://ncbi.nlm.nih.gov/pubmed/176461
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