Introduction of interrupted secondary structure in supercoiled DNA as a function of superhelix density: consideration of hairpin structures in superhelical DNA.

PM2 DNA was prepared with different superhelical densities (sigma) in order to examine the relationship betweenn supercoiling and the occurrence of a region(s) of unpaired bases in this DNA. A previous study showed that CH3HgOH reacts with native superhelical PM2 DNA more rapidly than the nicked for...

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Bibliographic Details
Main Authors: Woodworth-Gutai, M, Lebowitz, J
Format: Artigo
Language:Inglês
Published: 1976
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC515538/
https://ncbi.nlm.nih.gov/pubmed/1255870
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