Dorsal horn interneuron-derived Netrin-4 contributes to spinal sensitization in chronic pain via Unc5B

Because of the incomplete understanding of the molecular mechanisms that underlie chronic pain, the currently available treatments for this type of pain remain inefficient. In this study, we show that Netrin-4, a member of the axon guidance molecule family, was expressed in dorsal horn inner lamina...

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Bibliographic Details
Published in:J Exp Med
Main Authors: Hayano, Yasufumi, Takasu, Keiko, Koyama, Yoshihisa, Yamada, Moe, Ogawa, Koichi, Minami, Kazuhisa, Asaki, Toshiyuki, Kitada, Kazuhiro, Kuwabara, Satoshi, Yamashita, Toshihide
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154943/
https://ncbi.nlm.nih.gov/pubmed/27856613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160877
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