Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells

Although traditional chemotherapy kills a fraction of tumor cells, it also activates the stroma and can promote the growth and survival of residual cancer cells to foster tumor recurrence and metastasis. Accordingly, overcoming the host response induced by chemotherapy could substantially improve th...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Chan, Tze-Sian, Hsu, Chung-Chi, Pai, Vincent C., Liao, Wen-Ying, Huang, Shenq-Shyang, Tan, Kok-Tong, Yen, Chia-Jui, Hsu, Shu-Ching, Chen, Wei-Yu, Shan, Yan-Shen, Li, Chi-Rong, Lee, Michael T., Jiang, Kuan-Ying, Chu, Jui-Mei, Lien, Gi-Shih, Weaver, Valerie M., Tsai, Kelvin K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154935/
https://ncbi.nlm.nih.gov/pubmed/27881732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151665
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