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Triglyceride increase in the core of high-density lipoproteins augments apolipoprotein dissociation from the surface: Potential implications for treatment of apolipoprotein deposition diseases

Lipids in the body are transported via lipoproteins that are nanoparticles comprised of lipids and amphipathic proteins termed apolipoproteins. This family of lipid surface-binding proteins is over-represented in human amyloid diseases. In particular, all major proteins of high-density lipoproteins...

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Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: Jayaraman, Shobini, Sánchez-Quesada, Jose Luis, Gursky, Olga
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154891/
https://ncbi.nlm.nih.gov/pubmed/27768903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.10.010
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