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Prophylactic treatment with the tricyclic antidepressant desipramine prevents development of paclitaxel-induced neuropathic pain through activation of endogenous analgesic systems
Neuropathic pain impacts approximately 3–4.5% of the global population and remains an unresolved health problem. The management of neuropathic pain has two distinct goals—prevention of development and control of established neuropathic pain. We examined the impact of both prophylactic and therapeuti...
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| Veröffentlicht in: | Pharmacol Res |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5154848/ https://ncbi.nlm.nih.gov/pubmed/27773824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.10.007 |
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