Auranofin inactivates Trichomonas vaginalis thioredoxin reductase and is effective against trichomonads in vitro and in vivo

Trichomoniasis, caused by the protozoan parasite Trichomonas vaginalis, is the most common, non-viral, sexually transmitted infection in the world, but only two closely related nitro drugs are approved for its treatment. New antimicrobials against trichomoniasis remain an urgent need. Several organi...

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Опубликовано в: :Int J Antimicrob Agents
Главные авторы: Hopper, Melissa, Yun, Jeong-fil, Zhou, Bianhua, Le, Christine, Kehoe, Katelin, Le, Ryan, Hill, Ryan, Jongeward, Gregg, Debnath, Anjan, Zhang, Liangfang, Miyamoto, Yukiko, Eckmann, Lars, Land, Kirkwood M., Wrischnik, Lisa A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154799/
https://ncbi.nlm.nih.gov/pubmed/27839893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2016.09.020
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