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Integrins and heparan sulfate proteoglycans on hepatic stellate cells (HSC) are novel receptors for HSC-derived exosomes

Exosomes mediate intercellular microRNA delivery between hepatic stellate cells (HSC), the principal fibrosis-producing cells in the liver. The purpose of this study was to identify receptors on HSC for HSC-derived exosomes, which bind to HSC rather than to hepatocytes. Our findings indicate that ex...

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Publicat a:FEBS Lett
Autors principals: Chen, Li, Brigstock, David R
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154766/
https://ncbi.nlm.nih.gov/pubmed/27714787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12448
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