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Rapid and spontaneous loss of phthiocerol dimycocerosate (PDIM) from Mycobacterium tuberculosis grown in vitro: implications for virulence studies

Isolated in vitro more than half a century ago, the H37Rv strain of Mycobacterium tuberculosis still remains the strain of choice for the majority of laboratories conducting in vivo studies of TB pathogenesis. In this report we reveal that H37Rv is highly prone to losing the ability to synthesize th...

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Detalhes bibliográficos
Publicado no:Microbiology
Main Authors: Domenech, Pilar, Reed, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154741/
https://ncbi.nlm.nih.gov/pubmed/19661177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.029199-0
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