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Epithelial ovarian cancer inherent resistance: May the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role?

• Cancer cells may have inherent chemoresistance which allows an indefinite expansion. • Transformed ovarian epithelial cells may undergo an immunoediting process. • Immunoedited ovarian cancer drug-resistant cells escape first-line chemotherapy.

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Bibliographic Details
Published in:Gynecol Oncol Rep
Main Authors: Laganà, Antonio Simone, Sofo, Vincenza, Vitale, Salvatore Giovanni, Triolo, Onofrio
Format: Artigo
Language:Inglês
Published: Elsevier 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154672/
https://ncbi.nlm.nih.gov/pubmed/27995176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gore.2016.09.004
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