Functional Analyses of the Crohn’s Disease Risk Gene LACC1

BACKGROUND: Genetic variation in the Laccase (multicopper oxidoreductase) domain-containing 1 (LACC1) gene has been shown to affect the risk of Crohn’s disease, leprosy and, more recently, ulcerative colitis and juvenile idiopathic arthritis. LACC1 function appears to promote fatty-acid oxidation, w...

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Veröffentlicht in:PLoS One
Hauptverfasser: Assadi, Ghazaleh, Vesterlund, Liselotte, Bonfiglio, Ferdinando, Mazzurana, Luca, Cordeddu, Lina, Schepis, Danika, Mjösberg, Jenny, Ruhrmann, Sabrina, Fabbri, Alessia, Vukojevic, Vladana, Percipalle, Piergiorgio, Salomons, Florian A., Laurencikiene, Jurga, Törkvist, Leif, Halfvarson, Jonas, D’Amato, Mauro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154582/
https://ncbi.nlm.nih.gov/pubmed/27959965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168276
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