An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies

The response of human immunodeficiency virus type 1 (HIV-1) quasispecies to antiretroviral therapy is influenced by the ensemble of mutants that composes the evolving population. Low-abundance subpopulations within HIV-1 quasispecies may determine the viral response to the administered drug combinat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Martín, Verónica, Perales, Celia, Fernández-Algar, María, Dos Santos, Helena G., Garrido, Patricia, Pernas, María, Parro, Víctor, Moreno, Miguel, García-Pérez, Javier, Alcamí, José, Torán, José Luis, Abia, David, Domingo, Esteban, Briones, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154500/
https://ncbi.nlm.nih.gov/pubmed/27959928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166902
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