IL-22 exacerbates weight loss in a murine model of chronic pulmonary Pseudomonas aeruginosa infection

BACKGROUND: Interleukin (IL)-22 is a critical mediator of mucosal immunity and tissue regeneration, protecting against a number of respiratory pathogens. Whether IL-22 confers protection against chronic Pseudomonas aeruginosa (PA) infection in cystic fibrosis (CF) is unknown. METHODS: Explanted CF l...

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Publicat a:J Cyst Fibros
Autors principals: Bayes, Hannah K., Ritchie, Neil D., Ward, Christopher, Corris, Paul A., Brodlie, Malcolm, Evans, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154339/
https://ncbi.nlm.nih.gov/pubmed/27375092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2016.06.008
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