DNA-Minus Temperature-Sensitive Mutants of Adenovirus Type 5 Help Adenovirus-Associated Virus Replication

Efficient potentiation of adenovirus-associated viruses (AAV) replication occurs in coinfections with either of two DNA-minus temperature-sensitive mutants of adenovirus type 5 (Ad5), ts125 and ts149. The helper activity of these mutants does not result from leakiness. At the nonpermissive temperatu...

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Bibliographic Details
Main Authors: Straus, Stephen E., Ginsberg, Harold S., Rose, James A.
Format: Artigo
Language:Inglês
Published: 1976
Subjects:
Animal Viruses
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC515397/
https://ncbi.nlm.nih.gov/pubmed/1206799
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