Immediate tumor resection in patients with locally advanced gastroesophageal adenocarcinoma with nonresponse to chemotherapy after 4 weeks of treatment versus resection after completion of chemotherapy (OPTITREAT trial, DRKS00004668): study protocol for a randomized controlled pilot trial

BACKGROUND: Neoadjuvant chemotherapy is a standard of care for patients with adenocarcinoma of the esophagus and stomach in Europe, but still only 20–40 % respond to therapy and the critical issue; how to treat nonresponding patients is still unclear. So far, there is no randomized trial evaluating...

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Библиографические подробности
Опубликовано в: :Pilot Feasibility Stud
Главные авторы: Blank, Susanne, Knebel, Phillip, Haag, Georg-Martin, Bruckner, Thomas, Klaiber, Ulla, Burian, Maria, Schaible, Anja, Sisic, Leila, Schmidt, Thomas, Diener, Markus K., Ott, Katja
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Study Protocol
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153833/
https://ncbi.nlm.nih.gov/pubmed/27965838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40814-016-0059-x
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