Altered DNA methylation associated with an abnormal liver phenotype in a cattle model with a high incidence of perinatal pathologies

Cloning enables the generation of both clinically normal and pathological individuals from the same donor cells, and may therefore be a DNA sequence-independent driver of phenotypic variability. We took advantage of cattle clones with identical genotypes but different developmental abilities to inve...

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Publicado no:Sci Rep
Main Authors: Kiefer, Hélène, Jouneau, Luc, Campion, Évelyne, Rousseau-Ralliard, Delphine, Larcher, Thibaut, Martin-Magniette, Marie-Laure, Balzergue, Sandrine, Ledevin, Mireille, Prézelin, Audrey, Chavatte-Palmer, Pascale, Heyman, Yvan, Richard, Christophe, Le Bourhis, Daniel, Renard, Jean-Paul, Jammes, Hélène
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153653/
https://ncbi.nlm.nih.gov/pubmed/27958319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38869
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