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A Dynamical Threshold for Cardiac Delayed Afterdepolarization-Mediated Triggered Activity

Ventricular myocytes are excitable cells whose voltage threshold for action potential (AP) excitation is ∼−60 mV at which I(Na) is activated to give rise to a fast upstroke. Therefore, for a short stimulus pulse to elicit an AP, a stronger stimulus is needed if the resting potential lies further awa...

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Vydáno v:Biophys J
Hlavní autoři: Liu, Michael B., Ko, Christopher Y., Song, Zhen, Garfinkel, Alan, Weiss, James N., Qu, Zhilin
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153551/
https://ncbi.nlm.nih.gov/pubmed/27926853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.10.009
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