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Polarized Membrane Traffic and Cell Polarity Development Is Dependent on Dihydroceramide Synthase-Regulated Sphinganine Turnover

Sphingoid bases have been implicated in various cellular processes including cell growth, apoptosis and cell differentiation. Here, we show that the regulated turnover of sphingoid bases is crucial for cell polarity development, i.e., the biogenesis of apical plasma membrane domains, in well-differe...

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Autors principals: van IJzendoorn, Sven C.D., van der Wouden, Johanna M., Liebisch, Gerhard, Schmitz, Gerd, Hoekstra, Dick
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC515345/
https://ncbi.nlm.nih.gov/pubmed/15229289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-04-0290
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