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Evaluation of the Therapeutic Potential of the Novel Isotype Specific HDAC Inhibitor 4SC-202 in Urothelial Carcinoma Cell Lines

BACKGROUND: Targeting of class I histone deacetylases (HDACs) exerts antineoplastic actions in various cancer types by modulation of transcription, upregulation of tumor suppressors, induction of cell cycle arrest, replication stress and promotion of apoptosis. Class I HDACs are often deregulated in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Target Oncol
Prif Awduron: Pinkerneil, Maria, Hoffmann, Michèle J., Kohlhof, Hella, Schulz, Wolfgang A., Niegisch, Günter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer International Publishing 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153417/
https://ncbi.nlm.nih.gov/pubmed/27250763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-016-0444-7
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