Coiled-coil domain containing 68 (CCDC68) demonstrates a tumor suppressive role in pancreatic ductal adenocarcinoma

Using integrative genomics and functional screening we identified coiled-coil domain containing 68 (CCDC68) as a novel putative tumor suppressor (TSG) in pancreatic ductal adenocarcinoma (PDAC). CCDC68 allelic losses were documented in 48% of primary PDAC patient tumors, 50% of PDAC cell lines, and...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Radulovich, Nikolina, Leung, Lisa, Ibrahimov, Emin, Navab, Roya, Sakashita, Shingo, Zhu, Chang-Qi, Kaufman, Ethan, Lockwood, William W., Thu, Kelsie L., Fedyshyn, Yaroslav, Moffat, Jason, Lam, Wan L., Tsao, Ming-Sound
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153324/
https://ncbi.nlm.nih.gov/pubmed/25381825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.357
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