Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration

Mechanistic studies of axon growth during development are beneficial to the search for neuron-intrinsic regulators of axon regeneration. Here, we discovered that, in the developing neuron from rat, Akt signaling regulates axon growth and growth cone formation through phosphorylation of serine 14 (S1...

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Detalles Bibliográficos
Publicado en:eLife
Autores principales: Ko, Hyo Rim, Kwon, Il-Sun, Hwang, Inwoo, Jin, Eun-Ju, Shin, Joo-Ho, Brennan-Minnella, Angela M, Swanson, Raymond, Cho, Sung-Woo, Lee, Kyung-Hoon, Ahn, Jee-Yin
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153247/
https://ncbi.nlm.nih.gov/pubmed/27938661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20799
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