Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration

Mechanistic studies of axon growth during development are beneficial to the search for neuron-intrinsic regulators of axon regeneration. Here, we discovered that, in the developing neuron from rat, Akt signaling regulates axon growth and growth cone formation through phosphorylation of serine 14 (S1...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Ko, Hyo Rim, Kwon, Il-Sun, Hwang, Inwoo, Jin, Eun-Ju, Shin, Joo-Ho, Brennan-Minnella, Angela M, Swanson, Raymond, Cho, Sung-Woo, Lee, Kyung-Hoon, Ahn, Jee-Yin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2016
Konular:
Cell Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153247/
https://ncbi.nlm.nih.gov/pubmed/27938661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20799
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