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Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration

Mechanistic studies of axon growth during development are beneficial to the search for neuron-intrinsic regulators of axon regeneration. Here, we discovered that, in the developing neuron from rat, Akt signaling regulates axon growth and growth cone formation through phosphorylation of serine 14 (S1...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ko, Hyo Rim, Kwon, Il-Sun, Hwang, Inwoo, Jin, Eun-Ju, Shin, Joo-Ho, Brennan-Minnella, Angela M, Swanson, Raymond, Cho, Sung-Woo, Lee, Kyung-Hoon, Ahn, Jee-Yin
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153247/
https://ncbi.nlm.nih.gov/pubmed/27938661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20799
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