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Haplotype Analysis in Multiple Crosses to Identify a QTL Gene

Identifying quantitative trait locus (QTL) genes is a challenging task. Herein, we report using a two-step process to identify Apoa2 as the gene underlying Hdlq5, a QTL for plasma high-density lipoprotein cholesterol (HDL) levels on mouse chromosome 1. First, we performed a sequence analysis of the...

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Détails bibliographiques
Auteurs principaux: Wang, Xiaosong, Korstanje, Ron, Higgins, David, Paigen, Beverly
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC515323/
https://ncbi.nlm.nih.gov/pubmed/15310659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.2668204
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