Immunoprecipitation and Mass Spectrometry Defines an Extensive RBM45 Protein-Protein Interaction Network

The pathological accumulation of RNA-binding proteins (RBPs) within inclusion bodies is a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). RBP aggregation results in both toxic gain and loss of normal function. Determining the protein binding partners and...

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Bibliografiset tiedot
Julkaisussa:Brain Res
Päätekijät: Li, Yang, Collins, Mahlon, An, Jiyan, Geiser, Rachel, Tegeler, Tony, Tsantilas, Kristine, Garcia, Krystine, Pirrotte, Patrick, Bowser, Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5152586/
https://ncbi.nlm.nih.gov/pubmed/26979993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2016.02.047
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