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RBM45 homo-oligomerization mediates association with ALS-linked proteins and stress granules

The aggregation of RNA-binding proteins is a pathological hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). RBM45 is an RNA-binding protein that forms cytoplasmic inclusions in neurons and glia in ALS and FTLD. To explore the role of RBM45 in ALS and FTLD,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Yang, Collins, Mahlon, Geiser, Rachel, Bakkar, Nadine, Riascos, David, Bowser, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585734/
https://ncbi.nlm.nih.gov/pubmed/26391765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14262
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