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Immunoprecipitation and Mass Spectrometry Defines an Extensive RBM45 Protein-Protein Interaction Network
The pathological accumulation of RNA-binding proteins (RBPs) within inclusion bodies is a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). RBP aggregation results in both toxic gain and loss of normal function. Determining the protein binding partners and...
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Udgivet i: | Brain Res |
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Main Authors: | , , , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2016
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5152586/ https://ncbi.nlm.nih.gov/pubmed/26979993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2016.02.047 |
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