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Molecular markers of prognosis and therapeutic targets in metastatic colorectal cancer

Metastatic disease ultimately occurs in approximately 50–70% of patients presenting with colorectal cancer. In patients with advanced disease, there is significant variability in individual patient outcomes. To improve understanding of tumor behavior, markers such as KRAS and BRAF mutation status ar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Surg Oncol
Hauptverfasser: Ronnekleiv-Kelly, Sean M., Burkhart, Richard A., Pawlik, Timothy M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5152574/
https://ncbi.nlm.nih.gov/pubmed/27566022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.suronc.2016.05.018
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