Growth Differentiation Factor-15–Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells

PURPOSE: To determine the role and regulation of growth differentiation factor-15 (GDF-15), a TGF-β–related cytokine in human trabecular meshwork (TM) cells in the context of aqueous humor (AH) outflow and IOP. METHODS: Regulation of expression by external cues, and the distribution and secretion of...

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Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: Muralidharan, Arumugam Ramachandran, Maddala, Rupalatha, Skiba, Nikolai P., Rao, Ponugoti Vasantha
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2016
Témata:
Glaucoma
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5152563/
https://ncbi.nlm.nih.gov/pubmed/27918822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20671
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