Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.
The Fos/Jun and ATF/CREB families of transcription factors function in coupling extracellular signals to alterations in expression of specific target genes. Like many eukaryotic transcription factors, these proteins bind to DNA as dimers. Dimerization is mediated by a structure known as the "leucine...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1991
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1827203/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.9.3720 |
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