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Transcriptional Repressor CopR: Use of SELEX To Study the copR Operator Indicates that Evolution Was Directed at Maximal Binding Affinity

CopR is one of the two copy number control elements of the streptococcal plasmid pIP501. It represses transcription of the repR mRNA encoding the essential replication initiator protein about 10- to 20-fold by binding to its operator region upstream of the repR promoter pII. CopR binds at two consec...

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Detalhes bibliográficos
Main Authors: Freede, Peggy, Brantl, Sabine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC515161/
https://ncbi.nlm.nih.gov/pubmed/15342596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.18.6254-6264.2004
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