High-resolution structure of a picornaviral internal cis-acting RNA replication element (cre)

Picornaviruses constitute a medically important family of RNA viruses in which genome replication critically depends on a small RNA element, the cis-acting replication element (cre), that templates 3D(pol) polymerase-catalyzed uridylylation of the protein primer for RNA synthesis, VPg. We report the...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Thiviyanathan, Varatharasa, Yang, Yan, Kaluarachchi, Kumaralal, Rijnbrand, Rene, Gorenstein, David G., Lemon, Stanley M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC515117/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15314212/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403079101
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