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Tissue-specific codon usage and the expression of human genes

A diverse array of mechanisms regulate tissue-specific protein levels. Most research, however, has focused on the role of transcriptional regulation. Here we report systematic differences in synonymous codon usage between genes selectively expressed in six adult human tissues. Furthermore, we show t...

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Autors principals: Plotkin, Joshua B., Robins, Harlan, Levine, Arnold J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC515101/
https://ncbi.nlm.nih.gov/pubmed/15314228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404957101
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