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A gain-of-function mutation of Fgfr2c demonstrates the roles of this receptor variant in osteogenesis
The b and c variants of fibroblast growth factor receptor 2 (FGFR2) differ in sequence, binding specificity, and localization. Fgfr2b, expressed in epithelia, is required for limb outgrowth and branching morphogenesis, whereas the mesenchymal Fgfr2c variant is required by the osteocyte lineage for n...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC515096/ https://ncbi.nlm.nih.gov/pubmed/15316116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405031101 |
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