Granulocyte-Macrophage Colony-Stimulating Factor Enhancer Activation Requires Cooperation between NFAT and AP-1 Elements and Is Associated with Extensive Nucleosome Reorganization

The human granulocyte-macrophage colony-stimulating factor (GM-CSF) gene is activated by an NFAT-dependent enhancer forming an inducible DNase I hypersensitive (DH) site. The enhancer core comprising the DH site contains the GM330 and GM420 elements that bind NFAT and AP-1 cooperatively. Here we dem...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Johnson, Brett V., Bert, Andrew G., Ryan, Gregory R., Condina, Antony, Cockerill, Peter N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC515070/
https://ncbi.nlm.nih.gov/pubmed/15340054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.7914-7930.2004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados