A Single Pulse of Agrin Triggers a Pathway That Acts To Cluster Acetylcholine Receptors

Agrin triggers signaling mechanisms of high temporal and spatial specificity to achieve phosphorylation, clustering, and stabilization of postsynaptic acetylcholine receptors (AChRs). Agrin transiently activates the kinase MuSK; MuSK activation has largely vanished when AChR clusters appear. Thus, a...

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Detalhes bibliográficos
Main Authors: Mittaud, Peggy, Camilleri, Alain A., Willmann, Raffaella, Erb-Vögtli, Susanne, Burden, Steven J., Fuhrer, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC515067/
https://ncbi.nlm.nih.gov/pubmed/15340048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.7841-7854.2004
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