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A Single Pulse of Agrin Triggers a Pathway That Acts To Cluster Acetylcholine Receptors
Agrin triggers signaling mechanisms of high temporal and spatial specificity to achieve phosphorylation, clustering, and stabilization of postsynaptic acetylcholine receptors (AChRs). Agrin transiently activates the kinase MuSK; MuSK activation has largely vanished when AChR clusters appear. Thus, a...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC515067/ https://ncbi.nlm.nih.gov/pubmed/15340048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.7841-7854.2004 |
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