PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation

The rostromedial caudate (rmCD) of primates is thought to contribute to reward value processing, but a causal relationship has not been established. Here we use an inhibitory DREADD (Designer Receptor Exclusively Activated by Designer Drug) to repeatedly and non-invasively inactivate rmCD of macaque...

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Pubblicato in:Nat Commun
Autori principali: Nagai, Yuji, Kikuchi, Erika, Lerchner, Walter, Inoue, Ken-ichi, Ji, Bin, Eldridge, Mark A. G., Kaneko, Hiroyuki, Kimura, Yasuyuki, Oh-Nishi, Arata, Hori, Yukiko, Kato, Yoko, Hirabayashi, Toshiyuki, Fujimoto, Atsushi, Kumata, Katsushi, Zhang, Ming-Rong, Aoki, Ichio, Suhara, Tetsuya, Higuchi, Makoto, Takada, Masahiko, Richmond, Barry J., Minamimoto, Takafumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150653/
https://ncbi.nlm.nih.gov/pubmed/27922009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13605
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