Mice Deficient in the Axonemal Protein Tektin-t Exhibit Male Infertility and Immotile-Cilium Syndrome Due to Impaired Inner Arm Dynein Function

The haploid germ cell-specific Tektin-t protein is a member of the Tektin family of proteins that form filaments in flagellar, ciliary, and axonemal microtubules. To investigate the physiological role of Tektin-t, we generated mice with a mutation in the tektin-t gene. The homozygous mutant males we...

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Hlavní autoři: Tanaka, Hiromitsu, Iguchi, Naoko, Toyama, Yoshiro, Kitamura, Kouichi, Takahashi, Tohru, Kaseda, Kazuhiro, Maekawa, Mamiko, Nishimune, Yoshitake
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Mammalian Genetic Models with Minimal or Complex Phenotypes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC515054/
https://ncbi.nlm.nih.gov/pubmed/15340058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.7958-7964.2004
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