Lin28a promotes self-renewal and proliferation of dairy goat spermatogonial stem cells (SSCs) through regulation of mTOR and PI3K/AKT

Lin28a is a conserved RNA-binding protein that plays an important role in development, pluripotency, stemness maintenance, proliferation and self-renewal. Early studies showed that Lin28a serves as a marker of spermatogonial stem cells (SSCs) and promotes the proliferation capacity of mouse SSCs. Ho...

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Pubblicato in:Sci Rep
Autori principali: Ma, Fanglin, Zhou, Zhe, Li, Na, Zheng, Liming, Wu, Chongyang, Niu, Bowen, Tang, Furong, He, Xin, Li, Guangpeng, Hua, Jinlian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150521/
https://ncbi.nlm.nih.gov/pubmed/27941834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38805
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