Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA

HIV-1–infected individuals harbor a latent reservoir of infected CD4(+) T cells that is not eradicated by antiretroviral therapy (ART). This reservoir presents the greatest barrier to an HIV-1 cure and has remained difficult to characterize, in part, because the vast majority of integrated sequences...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Lorenzi, Julio C. C., Cohen, Yehuda Z., Cohn, Lillian B., Kreider, Edward F., Barton, John P., Learn, Gerald H., Oliveira, Thiago, Lavine, Christy L., Horwitz, Joshua A., Settler, Allison, Jankovic, Mila, Seaman, Michael S., Chakraborty, Arup K., Hahn, Beatrice H., Caskey, Marina, Nussenzweig, Michel C.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2016
主題:
PNAS Plus
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150408/
https://ncbi.nlm.nih.gov/pubmed/27872306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617789113
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