Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA

HIV-1–infected individuals harbor a latent reservoir of infected CD4(+) T cells that is not eradicated by antiretroviral therapy (ART). This reservoir presents the greatest barrier to an HIV-1 cure and has remained difficult to characterize, in part, because the vast majority of integrated sequences...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Lorenzi, Julio C. C., Cohen, Yehuda Z., Cohn, Lillian B., Kreider, Edward F., Barton, John P., Learn, Gerald H., Oliveira, Thiago, Lavine, Christy L., Horwitz, Joshua A., Settler, Allison, Jankovic, Mila, Seaman, Michael S., Chakraborty, Arup K., Hahn, Beatrice H., Caskey, Marina, Nussenzweig, Michel C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150408/
https://ncbi.nlm.nih.gov/pubmed/27872306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617789113
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