Human Immunodeficiency Virus Type 1 gp120 Induces Abnormal Maturation and Functional Alterations of Dendritic Cells: a Novel Mechanism for AIDS Pathogenesis

Dendritic cells (DCs) play a crucial role in bridging innate and acquired immune responses to pathogens. In human immunodeficiency virus type 1 (HIV-1) infection, immature DCs (iDCs) are also main targets for HIV-1 at the mucosal level. In this study, we evaluated the effects of HIV-1-DC interaction...

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Hlavní autoři: Fantuzzi, Laura, Purificato, Cristina, Donato, Karim, Belardelli, Filippo, Gessani, Sandra
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC515003/
https://ncbi.nlm.nih.gov/pubmed/15331709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.18.9763-9772.2004
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