N-Myc overexpression increases cisplatin resistance in neuroblastoma via deregulation of mitochondrial dynamics

N-Myc is a global transcription factor that regulates the expression of genes involved in a number of essential cellular processes including: ribosome biogenesis, cell cycle and apoptosis. Upon deregulation, N-Myc can drive pathologic expression of many of these genes, which ultimately defines its o...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Casinelli, Gabriella, LaRosa, Jeff, Sharma, Manika, Cherok, Edward, Banerjee, Swati, Branca, Maria, Edmunds, Lia, Wang, Yudong, Sims-Lucas, Sunder, Churley, Luke, Kelly, Samantha, Sun, Ming, Stolz, Donna, Graves, J Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149579/
https://ncbi.nlm.nih.gov/pubmed/28028439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.82
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