The Decay of Disease Association with Declining Linkage Disequilibrium: A Fine Mapping Theorem

Several important and fundamental aspects of disease genetics models have yet to be described. One such property is the relationship of disease association statistics at a marker site closely linked to a disease causing site. A complete description of this two-locus system is of particular importanc...

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Udgivet i:Front Genet
Main Authors: Maadooliat, Mehdi, Bansal, Naveen K., Upadhya, Jiblal, Farazi, Manzur R., Li, Xiang, He, Max M., Hebbring, Scott J., Ye, Zhan, Schrodi, Steven J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149547/
https://ncbi.nlm.nih.gov/pubmed/28018425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00217
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