Defective downregulation of receptor tyrosine kinases in cancer
Most growth factors control cellular functions by activating specific receptor tyrosine kinases (RTKs). While overactivation of RTK signalling pathways is strongly associated with carcinogenesis, it is becoming increasingly clear that impaired deactivation of RTKs may also be a mechanism in cancer....
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| Publicado no: | EMBO J |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514952/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15229652/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600292 |
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