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Ipilimumab for Patients with Relapse after Allogeneic Transplantation

BACKGROUND: Loss of donor-mediated immune antitumor activity after allogeneic hematopoietic stem-cell transplantation (HSCT) permits relapse of hematologic cancers. We hypothesized that immune checkpoint blockade established by targeting cytotoxic T-lymphocyte–associated protein 4 with ipilimumab co...

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Pubblicato in:N Engl J Med
Autori principali: Davids, Matthew S., Kim, Haesook T., Bachireddy, Pavan, Costello, Caitlin, Liguori, Rebecca, Savell, Alexandra, Lukez, Alexander P., Avigan, David, Chen, Yi-Bin, McSweeney, Peter, LeBoeuf, Nicole R., Rooney, Michael S., Bowden, Michaela, Zhou, Chensheng W., Granter, Scott R., Hornick, Jason L., Rodig, Scott J., Hirakawa, Masahiro, Severgnini, Mariano, Hodi, F. Stephen, Wu, Catherine J., Ho, Vincent T., Cutler, Corey, Koreth, John, Alyea, Edwin P., Antin, Joseph H., Armand, Philippe, Streicher, Howard, Ball, Edward D., Ritz, Jerome, Bashey, Asad, Soiffer, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149459/
https://ncbi.nlm.nih.gov/pubmed/27410923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1601202
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