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Biomimetic Approach to the Catalytic Enantioselective Synthesis of Flavonoids

Herein is reported the direct asymmetric addition of phenol nucleophiles to benzopyrylium salts as a means to produce enantioenriched flavonoid-like compounds. This enantioselective C–C bond construction was achieved through a chiral anion phase-transfer strategy that mimics the proposed biosynthesi...

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Publicat a:J Am Chem Soc
Autors principals: Yang, Zhenyu, He, Ying, Toste, F. Dean
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149420/
https://ncbi.nlm.nih.gov/pubmed/27472195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b05939
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