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CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells

The apoptosis-inducing death receptor CD95 (APO-1/Fas) controls the homeostasis of many tissues. Despite its apoptotic potential, most human tumors are refractory to the cytotoxic effects of CD95 ligand. We now show that CD95 stimulation of multiple apoptosis-resistant tumor cells by CD95 ligand ind...

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Autors principals: Barnhart, Bryan C, Legembre, Patrick, Pietras, Eric, Bubici, Concetta, Franzoso, Guido, Peter, Marcus E
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC514938/
https://ncbi.nlm.nih.gov/pubmed/15272306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600325
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