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Tumor suppressor IRF-1 mediates retinoid and interferon anticancer signaling to death ligand TRAIL
Retinoids and interferons are signaling molecules with pronounced anticancer activity. We show that in both acute promyelocytic leukemia and breast cancer cells the retinoic acid (RA) and interferon signaling pathways converge on the promoter of the tumoricidal death ligand TRAIL. Promoter mapping,...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514919/ https://ncbi.nlm.nih.gov/pubmed/15241475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600302 |
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