New Aspects of Silibinin Stereoisomers and their 3-O-galloyl Derivatives on Cytotoxicity and Ceramide Metabolism in Hep G(2) hepatocarcinoma Cell Line

Ceramide as a second messenger is a key regulator in apoptosis and cytotoxicity. Ceramide-metabolizing enzymes are ideal target in cancer chemo-preventive studies. Neutral sphingomyelinase (NSMase), acid ceramidase (ACDase) and glucosyl ceramide synthase (GCS) are the main enzymes in ceramide metabo...

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Bibliographic Details
Published in:Iran J Pharm Res
Main Authors: Mashhadi Akbar Boojar, Mahdi, Hassanipour, Mahsa, Ejtemaei Mehr, Shahram, Mashhadi Akbar Boojar, Masoud, Dehpour, Ahmad Reza
Format: Artigo
Language:Inglês
Published: Shaheed Beheshti University of Medical Sciences 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149029/
https://ncbi.nlm.nih.gov/pubmed/27980577
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