STAT3 signaling drives EZH2 transcriptional activation and mediates poor prognosis in gastric cancer

BACKGROUND: STAT3 signaling plays the pivotal role in tumorigenesis through EZH2 epigenetic modification, which enhanced STAT3 activity by increased tyrosine phosphorylation of STAT3. Here, another possible feedback mechanism and clinical significance of EZH2 and STAT3 were investigated in gastric c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Pan, Yuan-Ming, Wang, Cheng-Gang, Zhu, Min, Xing, Rui, Cui, Jian-Tao, Li, Wen-Mei, Yu, De-Dong, Wang, Shu-Bin, Zhu, Wei, Ye, Ying-Jiang, Wu, Yun, Wang, Shan, Lu, You-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148878/
https://ncbi.nlm.nih.gov/pubmed/27938379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0561-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados